Seminar (1)

Biomedical Image Informatics

David Breen

Drexel University

Abstract : The goal of biomedical image informatics is to develop techniques and systems that extract quantitative information from biomedical images and construct robust models of the structures and processes captured in the images. The word "images" is used in its broadest sense, meaning data that can be 2D, 3D or 4D in nature and changing over time. This talk will describe a number of image informatics projects conducted by the Drexel University Geometric Biomedical Computing Group. In the first project histology images of breast carcinomas are analyzed to determine if the tumor has metastasized. The second project developed techniques for automatically categorizing the memory and learning capabilities of a fruit fly model of Alzheimers Disease. This is accomplished via analysis of videos of the flies' courtship behavior. The final project generates geometric models of the individual cells of the imaginal wing disc of larval fruit flies, based on 3D reconstructions produced from confocal microscopy image stacks. Detailed geometric quantities about the cells are then computed in order to provide insight into the developmental processes that formed the wing disc.

Bio: David E. Breen is currently an Associate Professor in the Computer Science Department of Drexel University. He has held research positions at the Max Planck Institute for the Physics of Complex Systems, the California Institute of Technology, the European Computer-Industry Research Centre, the Fraunhofer Institute for Computer Graphics, and the Rensselaer Design Research Center. His research interests include biomedical image informatics, computer-aided design, geometric modeling, self-organization and biological simulation. He has authored or co-authored over 100 technical papers, articles and book chapters on these and other subjects. He is the co-editor of the book "Cloth Modeling and Animation". Breen received a BA in Physics from Colgate University in 1982. He received MS and PhD degrees in Computer and Systems Engineering from Rensselaer Polytechnic Institute in 1985 and 1993.

Date: 2017-May-12     Time: 11:30:00     Room: 020