Understanding Bio-Complexity with Signal Processing
Gail Rosen,
Georgia Institute of Technology –
Abstract:
Using signal processing, we wish to gain knowledge about biological complexity, as well as using this knowledge to engineer better technology. Three areas are identified as critical to understanding bio-complexity: 1) understanding DNA, 2) understanding protein pathways, and 3) evaluating overall biological function subject to external conditions. First, DNA is investigated for coding structure and redundancy, and a new tandem repeat region, an indicator of a neurodegenerative disease, is discovered. Second, the way a single-cell mobilizes in response to a chemical gradient, known as chemotaxis, is examined. Inspiration from chemotaxis receptor clustering is shown to improve sensor array performance of a gradient-source (chemical/thermal) localization algorithm. Implementation of the array is evaluated in diffusive and turbulent environments. We also show how to improve sensor array localization in turbulence by using the cross-correlation method. The work illustrates how signal processing is a tool to reverse engineer complex biological systems, and how our better understanding of biology can improve sensor network localization.
Date: 2006-Feb-10 Time: 15:00:00 Room: 425
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Upcoming Events
INESC Brussels HUB Winter Meeting 2023

This edition of the HUB Winter Meeting will be co-organised with Science Business and will take place on the 30 and 31 January, in Lisbon, at Instituto Superior Técnico, Department of Computer Science and Engineering.
Please see below a summary of the agenda, this will be updated on the INESC Brussels HUB website regularly (confirmed speakers and other relevant info). Places for onsite participation are limited so registration is mandatory. Online participants will be sent a ZOOM link for each specific session on the 27th January.
INESC Brussels HUB website: https://hub.inesc.pt/
Monday, 30 January
a) Digital Europe Programme & Chips Act: state of play and possibilities for INESC.
9h to 10h30 GMT
(Exclusive for INESC researchers and administrators).
b) Science Business: how can INESC tap into Science Business network, activities and communications tools.
(Exclusive for INESC researchers and administrators).
c) Networking Lunch (for all onsite participants).
d) Roundtable: From rhetoric to reality – Embedding international strategy in the DNA of research organisations.
(Closed-door, roundtable workshop, Chatham House rules, open to INESC researchers and administrators, external participants by invitation only).
e) Networking Dinner
(By invitation only – INESC researchers participating onsite in the event are elegible to join).
Tuesday, 31 January
f) Workshop: How they did it? Strategic positioning for structural success in Horizon Europe: a discussion of best practices.
(Exclusive for INESC researchers, administrators and international invited speakers).
g) The public consultation on European R&I Programmes: Towards FP10.
(Closed-door, roundtable workshop, Chatham House rules, open to INESC researchers and administrators, external participants by invitation only).
h) Networking Lunch (for all onsite participants).
i) Management Committee meeting (Directors and POB members)
The HUB Winter Meeting aims at bringing together researchers and administrators from the 5 INESC institutes, affiliated higher education institutions in Portugal and abroad, with key European and global players, to:
– Discuss key research and innovation issues at EU level.
– Inform institutional policy and strategy.
– Exchange best-practices about R&I management, career development and policy positioning.
– Promote, discuss and deliver vision, visibility, networking and impactful communication.
– Create, identify and deepen partnerships and collaboration opportunities for collaborative R&I.