A Computational Device Based on Regulation
Universidade de Coimbra –
Nature is a great designer and problem solver. The theories posit by Darwin, Mendel and all those that contributed for the modern synthesis, based on molecular biology, explained us how this could happen. Some decades ago, computer scientists start proposing computational models, called evolutionary algorithms, based on some of the processes used by nature, in order to solve problems that either do not have an analytical solution or are to costly if we apply exact methods. Along time, many complex problems were satisfactory solved by those algorithms, even if those nature-inspired heuristic methods are very simplistic, and based on a basic separation between the genotype and the phenotype. In recent years, the biologic understanding was increased with the comprehension of the multitude of regulatory mechanisms that are fundamental in both processes of inheritance and of development, and some researchers advocate the need to explore computationally this new understanding. One of the outcomes was the Artificial Gene Regulatory model, first proposed by Wolfgang Banzhaf. In this talk, we will present a modification of this model, aimed at solving some of its limitations, and show experimentally that it is effective in solving a set of benchmark problems. We will also discuss some future developments of the model.
Date: 2011-Jan-14 Time: 14:00:00 Room: 336
For more information:
Workshop “Metabolism and mathematical models: Two for a tango” – 2nd Edition
Title: Workshop Metabolism and mathematical models: Two for a tango – 2nd Edition
Dates: October 25-26, 2022
Location: This workshop will be held in a virtual way
The topic of this workshop is metabolism in general, with a special focus, although not exclusive, on parasitology. Besides an exploration of the biological, biochemical and biomedical aspects, the workshop will also aim at presenting some of the mathematical modelling, algorithmic theory and software development that have become crucial to explore such aspects.
This workshop is being organised in the context of two projects, both with the Inria European Team Erable. One of the projects involves a partnership with the University of São Paulo (USP), in São Paulo, Brazil, more specifically the Institute of Mathematics and Statistics (IME) and the Institute of Biomedical Sciences – Inria Associated Team Capoeira – and the other involves the Inesc-ID/IST in Portugal, ETH in Zürich and EMBL in Heidelberg – H2020 Twinning Project Olissipo.
The workshop is open to all members of these two projects but also, importantly, to the community in general.
The program and more details are available here.