Dynamic neuroimaging using EEG-fMRI
It has recently become possible to record the EEG simultaneously with fMRI, providing whole-brain maps of the hemodynamic (fMRI) correlates of electrophysiological (EEG) activity. The combination of the EEG high temporal resolution with the fMRI high spatial resolution offers a unique opportunity for studying the spatio-temporal dynamics of brain activity noninvasively. Here, I will focus on the application of EEG-fMRI to the study of spontaneous epileptic activity in patients undergoing pre-surgical evaluation. The EEG is used to identify electrical discharges associated with epileptic seizures, as well as interictal epileptiform spikes, and the fMRI correlates of such EEG features can then be used to localize the brain networks involved in the epileptic activity. I will first introduce the basic principles and main challenges of the EEG-fMRI technique. I will then present results regarding the investigation of the link between EEG and fMRI signals, as well as the functional brain connectivity underlying seizure propagation. Appropriate biophysically-inspired models are employed in order to extract the relevant information from the EEG-fMRI data. It is shown that, in this way, important insights may be gained into the spatio-temporal dynamics of epileptic activity.
Date: 2012-Apr-27 Time: 14:30:00 Room: 020
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Workshop “Metabolism and mathematical models: Two for a tango” – 2nd Edition
Title: Workshop Metabolism and mathematical models: Two for a tango – 2nd Edition
Dates: October 25-26, 2022
Location: This workshop will be held in a virtual way
The topic of this workshop is metabolism in general, with a special focus, although not exclusive, on parasitology. Besides an exploration of the biological, biochemical and biomedical aspects, the workshop will also aim at presenting some of the mathematical modelling, algorithmic theory and software development that have become crucial to explore such aspects.
This workshop is being organised in the context of two projects, both with the Inria European Team Erable. One of the projects involves a partnership with the University of São Paulo (USP), in São Paulo, Brazil, more specifically the Institute of Mathematics and Statistics (IME) and the Institute of Biomedical Sciences – Inria Associated Team Capoeira – and the other involves the Inesc-ID/IST in Portugal, ETH in Zürich and EMBL in Heidelberg – H2020 Twinning Project Olissipo.
The workshop is open to all members of these two projects but also, importantly, to the community in general.
The program and more details are available here.