Unravelling communities of ALS patients using network mining
André Carreiro,
Departamento de Engenharia Informática –
Abstract:
Amyotrophic Lateral Sclerosis is a devastating neurodegenerative
disease characterized by a usually fast progression of
muscular denervation, generally leading to death in a few
years from onset. In this context, any significant improvement
of the patients life expectancy and quality is of major
relevance. Several studies have been made to address problems
such as ALS diagnosis, and more recently, prognosis.
However, these analysis have been mostly restricted to classical
statistical approaches used to find the most associated
features to a given outcome of interest. In this work we explore
an innovative approach to the analysis of clinical data characterized
by multivariate time series. We use a distance measure
between patients as a reflection of their relationship, to
build a patients network, which in turn can be studied from
a modularity point of view, in order to search for communities,
or groups of similar patients. The preliminary results
show that it is possible to extract relevant information from
such groups, each presenting a particular behavior for some
of the features (patient characteristics) under analysis.
Date: 2013-Jun-21 Time: 11:00:00 Room: 336
For more information:
- http://kdbio.inesc-id.pt/cms/
- lsr@kdbio.inesc-id.pt
- (+351) 21 31 00272
Upcoming Events
INESC Brussels HUB Winter Meeting 2023

This edition of the HUB Winter Meeting will be co-organised with Science Business and will take place on the 30 and 31 January, in Lisbon, at Instituto Superior Técnico, Department of Computer Science and Engineering.
Please see below a summary of the agenda, this will be updated on the INESC Brussels HUB website regularly (confirmed speakers and other relevant info). Places for onsite participation are limited so registration is mandatory. Online participants will be sent a ZOOM link for each specific session on the 27th January.
INESC Brussels HUB website: https://hub.inesc.pt/
Monday, 30 January
a) Digital Europe Programme & Chips Act: state of play and possibilities for INESC.
9h to 10h30 GMT
(Exclusive for INESC researchers and administrators).
b) Science Business: how can INESC tap into Science Business network, activities and communications tools.
(Exclusive for INESC researchers and administrators).
c) Networking Lunch (for all onsite participants).
d) Roundtable: From rhetoric to reality – Embedding international strategy in the DNA of research organisations.
(Closed-door, roundtable workshop, Chatham House rules, open to INESC researchers and administrators, external participants by invitation only).
e) Networking Dinner
(By invitation only – INESC researchers participating onsite in the event are elegible to join).
Tuesday, 31 January
f) Workshop: How they did it? Strategic positioning for structural success in Horizon Europe: a discussion of best practices.
(Exclusive for INESC researchers, administrators and international invited speakers).
g) The public consultation on European R&I Programmes: Towards FP10.
(Closed-door, roundtable workshop, Chatham House rules, open to INESC researchers and administrators, external participants by invitation only).
h) Networking Lunch (for all onsite participants).
i) Management Committee meeting (Directors and POB members)
The HUB Winter Meeting aims at bringing together researchers and administrators from the 5 INESC institutes, affiliated higher education institutions in Portugal and abroad, with key European and global players, to:
– Discuss key research and innovation issues at EU level.
– Inform institutional policy and strategy.
– Exchange best-practices about R&I management, career development and policy positioning.
– Promote, discuss and deliver vision, visibility, networking and impactful communication.
– Create, identify and deepen partnerships and collaboration opportunities for collaborative R&I.