David Breen,

Drexel University


The goal of biomedical image informatics is to develop techniques
and systems that extract quantitative information from biomedical
images and construct robust models of the structures and processes
captured in the images. The word “images” is used in its broadest
sense, meaning data that can be 2D, 3D or 4D in nature and changing
over time. This talk will describe a number of image informatics
projects conducted by the Drexel University Geometric Biomedical
Computing Group. In the first project histology images of breast
carcinomas are analyzed to determine if the tumor has metastasized.
The second project developed techniques for automatically categorizing
the memory and learning capabilities of a fruit fly model of Alzheimers
Disease. This is accomplished via analysis of videos of the flies’
courtship behavior. The final project generates geometric models of
the individual cells of the imaginal wing disc of larval fruit flies,
based on 3D reconstructions produced from confocal microscopy image
stacks. Detailed geometric quantities about the cells are then computed
in order to provide insight into the developmental processes that formed
the wing disc.


David E. Breen is currently an Associate Professor in the Computer
Science Department of Drexel University. He has held research positions
at the Max Planck Institute for the Physics of Complex Systems, the
California Institute of Technology, the European Computer-Industry
Research Centre, the Fraunhofer Institute for Computer Graphics, and
the Rensselaer Design Research Center. His research interests include
biomedical image informatics, computer-aided design, geometric modeling,
self-organization and biological simulation. He has authored or
co-authored over 100 technical papers, articles and book chapters on
these and other subjects. He is the co-editor of the book “Cloth Modeling
and Animation”. Breen received a BA in Physics from Colgate University
in 1982. He received MS and PhD degrees in Computer and Systems
Engineering from Rensselaer Polytechnic Institute in 1985 and 1993.


Date: 2017-May-12     Time: 11:30:00     Room: 020

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