A MAGNETORESISTIVE BIOCHIP FOR WATERBORN PATHOGEN DETECTION
Center for Biological and Chemical Engineering (CEBQ) – IST –
Microbial pathogen detection is of utmost importance for clinical diagnosis, food safety, water quality control and bioterrorism issues. Often is critical to have bacterial detection results as fast as possible in order to prevent public health issues or eliminate or minimize contamination.
Traditional methods, mostly based on plate counting, are slow, relatively expensive and are unable to provide high throughput screening.
A magnetoresistive biochip is being developed at INESC –MN and CEBQ-IST as a biosensor for pathogen detection. This system enables a very fast detection of bacteria by combining hard-disk read-head sensing and electronics with specific probes functionalised surfaces and functionalised magnetic nanoparticles.
The magnetoresistive biochip is well suited for pathogen detection when fast, accurate, sensitive and high-throughput responses are required, such as when determining the bacterial strain present in a lung infection; evaluating if a beef sample is free of Salmonella and is suitable for dispatching for consumption; to inquire for the presence of E. coli in drinking water and early detect the presence of bioterrorism agents like anthrax. In all these cases, time is a crucial factor and the earliest the detection is performed the sooner the effects of bacterial infection or contamination can be eliminated or minimized.
Although the magnetoresistive biosensor technology can be used with equal efficiency in pathogen detection in several fields, the first target for this system will be in water quality management for control and monitorization of microbial pathogens in water supplies for human consumption.
Date: 2006-Jan-17 Time: 14:00:00 Room: 336
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Workshop “Metabolism and mathematical models: Two for a tango” – 2nd Edition
Title: Workshop Metabolism and mathematical models: Two for a tango – 2nd Edition
Dates: October 25-26, 2022
Location: This workshop will be held in a virtual way
The topic of this workshop is metabolism in general, with a special focus, although not exclusive, on parasitology. Besides an exploration of the biological, biochemical and biomedical aspects, the workshop will also aim at presenting some of the mathematical modelling, algorithmic theory and software development that have become crucial to explore such aspects.
This workshop is being organised in the context of two projects, both with the Inria European Team Erable. One of the projects involves a partnership with the University of São Paulo (USP), in São Paulo, Brazil, more specifically the Institute of Mathematics and Statistics (IME) and the Institute of Biomedical Sciences – Inria Associated Team Capoeira – and the other involves the Inesc-ID/IST in Portugal, ETH in Zürich and EMBL in Heidelberg – H2020 Twinning Project Olissipo.
The workshop is open to all members of these two projects but also, importantly, to the community in general.
The program and more details are available here.