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  • Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning
    Zhaoxiang Cai, Sofia Apolinário, Ana Rita Baião, Pacini Clare, Miguel Dinis Madeira Agostinho de Sousa, Susana Vinga, Roger R Reddel, Phillip J Robinson, Mathew J. Garnett, Qing Zhong, Emanuel Gonçalves
    Nature Communications
    2024
  • A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
    Pacini Clare, Emma Duncan, Emanuel Gonçalves, James Gilbert, Shriram Bhosle, Stuart Horswell, Emre Karakoc, Howard Lightfoot, Ed Curry, Francesc Muyas, Monsif Bouaboula, Chandra Sekhar Pedamallu, Isidro Cortes-Ciriano, Fiona Behan, Lykourgos-Panagiotis Zalmas, Syd Barthorpe, Hayley E. Francies, Steve Rowley, Jack Pollard, Pedro Beltrão, Leopold Parts, Francesco Iorio, Mathew J. Garnett
    Cancer Cell
    2024
  • Base editing screens map mutations affecting interferon-γ signaling in cancer
    Matthew A.Coelho, Sarah Cooper, Magdalena E. Strauss, Emre Karakoc, Shriram Bhosle, Emanuel Gonçalves, Gabriele Picco, Thomas Burgold, Chiara M. Cattaneo, Vivien Veninga, Sarah Consonni, Cansu Dinçer, Sara F. Vieira, Freddy Gibson, Syd Barthorpe, Claire Hardy, Joel Rein, Mark Thomas, John Marioni, Emile E. Voest, Andrew Bassett, Mathew J. Garnett
    Cancer Cell DOI https://doi.org/10.1016/j.ccell.2022.12.009
    2023
  • Pan-cancer proteomic map of 949 human cell lines
    Emanuel Gonçalves, Rebecca C Poulos, Zhaoxiang Cai, Syd Barthorpe, Srikanth S Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker, Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G Williams, Yangxiu Wu, Dylan Xavier, Karen L MacKenzie, Peter G Hains, Brett Tully, Phillip J Robinson, Qing Zhong, Mathew J. Garnett, Roger R Reddel
    Cancer Cell vol. 40, DOI https://doi.org/10.1016/j.ccell.2022.06.010
    2022
  • A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens
    Stacey Price, Shriram Bhosle, Emanuel Gonçalves, Xiaodun Li, Dylan P. McClurg, Syd Barthorpe, Alex Beck, Caitlin Hall, Howard Lightfoot, Luke Farrow, Rizwan Ansari, David A. Jackson, Laura Allen, Kirsty Roberts, Charlotte Beaver, Hayley E. Francies, Mathew J. Garnett
    Scientific Reports vol. 12, DOI https://doi.org/10.1038/s41598-022-09508-y
    2022

Keywords

Year Published

2022 - 2024

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(5)
Journal Paper

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